Abstract
An advanced Surface-Enhanced Raman Scattering (SERS) Nanosensor Array, dedicated
to serve in the future as a pH imager for the real-time detection of chemical reaction, is presented.
The full flow of elementary steps—architecture, design, simulations, fabrication, and preliminary
experimental results of structural characterization (Focused Ion Beam (FIB), TEM and SEM)—show an
advanced SERS pixel array that is capable of providing spatially resolved measurements of chemical
pH in a fluid target that became more than desirable in this period. Ultimately, the goal will be to
provide real-time monitoring of a chemical reaction. The pixels consist of a nanostructured substrate
composed of an array of projections or cavities. The shape of the nanostructures and the thickness of
the metallic (Ag or Au) layer can be tuned to give maximal enhancement at the desired wavelength.
The number and arrangement of nanostructures is optimized to obtain maximal responsivity